AACN Certification Practice Test 2025 – Comprehensive Exam Prep

Question: 1 / 400

What is an absolute contraindication to fibrinolysis?

History of transient ischemic attack

Severe hypertension (BP >180/110)

Severe hypertension, defined as a blood pressure reading greater than 180/110 mmHg, is considered an absolute contraindication to fibrinolysis. This is because elevated blood pressure increases the risk of hemorrhagic complications, particularly in the context of administering fibrinolytic therapy. Fibrinolytics work by breaking down clots, but in a patient with severely high blood pressure, the likelihood of bleeding, particularly intracranially, escalates significantly.

In cases of severe hypertension, the potential benefits of fibrinolysis are overshadowed by the risks associated with uncontrolled blood pressure. Managing blood pressure appropriately before considering fibrinolytic therapy is crucial to ensure patient safety. This contraindication is established in clinical guidelines to prevent adverse outcomes related to bleeding risks associated with fibrinolysis in patients with significant hypertension.

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Age over 70 years

Diabetes mellitus

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