AACN Certification Practice Test 2026 – Comprehensive Exam Prep

ACE inhibitors are primarily classified as antihypertensive agents because they specifically target the renin-angiotensin-aldosterone system, which plays a crucial role in regulating blood pressure. By inhibiting the angiotensin-converting enzyme (ACE), these medications prevent the conversion of angiotensin I to angiotensin II, a powerful vasoconstrictor. This action leads to vasodilation, reduced blood volume, and therefore a lowering of blood pressure.

Antihypertensive agents, such as ACE inhibitors, are critical in the management of hypertension and are often used for treating heart failure, chronic kidney disease, and diabetes-related conditions, as they also provide renal protection. The other categories listed do not reflect the primary action and therapeutic use of ACE inhibitors; beta-blockers are primarily used to reduce heart rate and myocardial workload, calcium channel blockers primarily manage angina and arrhythmias, and cholesterol medications aim to lower lipid levels in the blood.